PRODUCTS
We combine peptide science, manufacturing capability and cosmetic application expertise to help customers create innovative beauty products.
Expression-Line Peptide
Cosdermo™ SpilaLift™
INCI
Spilanthoyl sh-Hexapeptide-46 SP Amide
Applications
Facial Care · Eye Care
Certifications & IP
Available Formats
Powder
White to off-white powder
Solution
Colorless to pale yellow clear liquid
Key Benefits
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Mechanism of Action
Cosdermo® SpilaLift helps modulate neuromuscular signaling by competitively interfering with SNARE complex formation and neuronal impulse transmission. This can reduce excessive acetylcholine release associated with facial muscle contraction, supporting a smoother appearance of dynamic expression lines.
Efficacy Data
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In Vivo:At 5%, delivers immediate (30-minute) and long-lasting (28-day) improvement in the appearance of facial wrinkles, together with improvement in skin elasticity. |
In Vitro:Helps reduce muscle contraction-related signaling through inhibition of acetylcholine release. Demonstrates rapid epidermal penetration within 4 hours. |
Technical Information | 500 ppm Solution
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Parameter |
Information |
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INCI Name |
Spilanthoyl sh-Hexapeptide-46 SP Amide |
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Product Form |
Colorless to pale yellow clear liquid |
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Nominal Concentration |
500 ppm |
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Solubility |
Water-soluble |
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Storage |
Store in a dry, dark place at 2–8°C for long-term storage. |
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Transportation |
Can be transported at room temperature. |
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Availability |
Detailed technical information is available upon request. |
Formulation Guide
Recommended Use Level
1–10%
Detailed Formulation Guidance
Available upon request.
Quality You Can Trust
Backed by 13 years of peptide R&D and manufacturing experience, Cosdermo® combines scientific expertise with robust quality-control capabilities to provide customers with consistent quality, reliable supply and traceable production. Our quality, environmental, occupational health & safety and responsible sourcing systems are supported by EFFCI GMP, ISO 9001, ISO 14001 and ISO 45001, together with RSPO certification and an EcoVadis Silver Medal.
| 13 Years of Peptide Expertise Established peptide R&D and manufacturing capabilities. | Certified Quality & Operations EFFCI GMP · ISO 9001 · ISO 14001 · ISO 45001 | Responsible & Sustainable Supply RSPO · EcoVadis Silver Medal · Traceable production |
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Expression-Line Care
Neuromuscular Signaling
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