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Expression-Line Peptide

Cosdermo™ Arginine/Lysine Polypeptide

A cosmetic polypeptide designed to support expression-line care through complementary modulation of acetylcholine receptor signaling and muscle-fiber sodium-channel activity.

INCI

Arginine/Lysine Polypeptide

Applications

Facial Care · Eye Care

Certifications & IP

Other Products

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Available Formats

Powder

≥95% purity
Powder format

Solution

Available
Formulation-ready solution

Key Benefits

Expression-Line Care

Supports a smoother appearance of dynamic expression lines.

Dual Neuromodulating Action

Helps limit acetylcholine binding while modulating Nav1.4 sodium-channel activity associated with muscle stimulation.

Facial Relaxation & Smoothness

Helps reduce excessive facial muscle stimulation for a more relaxed, smoother-looking complexion.

Mechanism of Action

Arginine/Lysine Polypeptide works through a dual neuromodulating mechanism. It competitively interferes with acetylcholine binding to receptor α-subunits, helping reduce excessive muscle stimulation. It also modulates Nav1.4 sodium channels in muscle fibers, limiting sodium influx and postsynaptic action potential formation. Together, these actions help relax facial tension and support a smoother appearance of dynamic expression lines.

Efficacy Data

In Vitro:

Helps reduce muscle contraction-related signaling by inhibiting acetylcholine release and modulating neuronal activity.

Powder Solution

Technical Information | Powder

Parameter	Information
INCI Name	Arginine/Lysine Polypeptide
Purity	≥95.0%
Solubility	Water-soluble
Availability	Detailed technical information is available upon request.

Formulation Guide

Detailed formulation guidance is available upon request.

Technical Information | Solution

Parameter	Information
INCI Name	Arginine/Lysine Polypeptide
Product Form	Solution
Solubility	Water-soluble
Availability	Detailed technical information is available upon request.

Formulation Guide

Recommended Use Level

1–8%

Detailed Formulation Guidance

Available upon request.

Quality You Can Trust

Backed by 13 years of peptide R&D and manufacturing experience, Cosdermo® combines scientific expertise with robust quality-control capabilities to provide customers with consistent quality, reliable supply and traceable production. Our quality, environmental, occupational health & safety and responsible sourcing systems are supported by EFFCI GMP, ISO 9001, ISO 14001 and ISO 45001, together with RSPO certification and an EcoVadis Silver Medal.

13 Years of Peptide Expertise Established peptide R&D and manufacturing capabilities.

Certified Quality & Operations EFFCI GMP · ISO 9001 · ISO 14001 · ISO 45001

Responsible & Sustainable Supply RSPO · EcoVadis Silver Medal · Traceable production

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